Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44

Cancer stem cells (CSCs) or tumor progenitor cells are involved in tumor progression and metastasis1. MicroRNAs (miRNAs) regulate both normal stem cells and CSCs2–5 and miRNA dysregulation has been implicated in tumorigenesis6. CSCs in many tumors, including cancers of the breast7, pancreas8, head a...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Can, Kelnar, Kevin, Liu, Bigang, Chen, Xin, Calhoun-Davis, Tammy, Li, Hangwen, Patrawala, Lubna, Yan, Hong, Jeter, Collene, Honorio, Sofia, Wiggins, Jason F., Bader, Andreas G., Fagin, Randy, Brown, David, Tang, Dean G.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076220/
https://www.ncbi.nlm.nih.gov/pubmed/21240262
http://dx.doi.org/10.1038/nm.2284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076220/
https://www.ncbi.nlm.nih.gov/pubmed/21240262
http://dx.doi.org/10.1038/nm.2284

Ejemplares similares