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The Rostral Migratory Stream Plays a Key Role in Intranasal Delivery of Drugs into the CNS

BACKGROUND: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into the CNS. So far, the anatomical s...

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Detalles Bibliográficos
Autores principales: Scranton, Robert A., Fletcher, Lauren, Sprague, Shane, Jimenez, David F., Digicaylioglu, Murat
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076435/
https://www.ncbi.nlm.nih.gov/pubmed/21533252
http://dx.doi.org/10.1371/journal.pone.0018711