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The Rostral Migratory Stream Plays a Key Role in Intranasal Delivery of Drugs into the CNS
BACKGROUND: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path for efficient drug delivery into the CNS. So far, the anatomical s...
Autores principales: | Scranton, Robert A., Fletcher, Lauren, Sprague, Shane, Jimenez, David F., Digicaylioglu, Murat |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076435/ https://www.ncbi.nlm.nih.gov/pubmed/21533252 http://dx.doi.org/10.1371/journal.pone.0018711 |
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