Mechanics of the IL2RA Gene Activation Revealed by Modeling and Atomic Force Microscopy

Transcription implies recruitment of RNA polymerase II and transcription factors (TFs) by DNA melting near transcription start site (TSS). Combining atomic force microscopy and computer modeling, we investigate the structural and dynamical properties of the IL2RA promoter and identify an intrinsical...

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Detalles Bibliográficos
Autores principales: Milani, Pascale, Marilley, Monique, Sanchez-Sevilla, Albert, Imbert, Jean, Vaillant, Cédric, Argoul, Françoise, Egly, Jean-Marc, Rocca-Serra, José, Arneodo, Alain
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076448/
https://www.ncbi.nlm.nih.gov/pubmed/21533205
http://dx.doi.org/10.1371/journal.pone.0018811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076448/
https://www.ncbi.nlm.nih.gov/pubmed/21533205
http://dx.doi.org/10.1371/journal.pone.0018811

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