RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses

The ability of oncolytic adenoviruses to replicate in and lyse cancer cells offers a potential therapeutic approach. However, selectivity and efficacy of adenovirus replication need to be improved. In this study, we present that loss of p21(WAF1) promotes adenovirus replication and more effective ce...

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Detalles Bibliográficos
Autores principales: Shiina, M, Lacher, M D, Christian, C, Korn, W M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076587/
https://www.ncbi.nlm.nih.gov/pubmed/19407849
http://dx.doi.org/10.1038/cgt.2009.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076587/
https://www.ncbi.nlm.nih.gov/pubmed/19407849
http://dx.doi.org/10.1038/cgt.2009.29

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