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Structure of the VP16 Transactivator Target in ARC/Mediator

The human Activator-Recruited Cofactor (ARC)/Mediator co-activator complex interacts with many transcriptional activators and facilitates recruitment of RNA polymerase II to promote target gene transcription. The MED25 (ARC92) subunit is a critical target of the potent Herpes simplex 1 viral transcr...

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Detalles Bibliográficos
Autores principales: Milbradt, Alexander G., Kulkarni, Madhura, Yi, Tingfang, Takeuchi, Koh, Sun, Zhen-Yu J., Luna, Rafael E., Selenko, Philipp, Näär, Anders M., Wagner, Gerhard
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076674/
https://www.ncbi.nlm.nih.gov/pubmed/21378963
http://dx.doi.org/10.1038/nsmb.1999