Asymmetric Cell Divisions Promote Notch-Dependent Epidermal Differentiation

Stem and progenitor cells utilize asymmetric cell divisions to balance proliferation and differentiation. Evidence from lower eukaryotes shows that this process is regulated by proteins asymmetrically distributed at the cell cortex during mitosis: (1) Par3-Par6-aPKC, conferring polarity; (2) Gαi-LGN...

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Detalles Bibliográficos
Autores principales: Williams, Scott E., Beronja, Slobodan, Pasolli, H. Amalia, Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077085/
https://www.ncbi.nlm.nih.gov/pubmed/21331036
http://dx.doi.org/10.1038/nature09793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077085/
https://www.ncbi.nlm.nih.gov/pubmed/21331036
http://dx.doi.org/10.1038/nature09793

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