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MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis

A major feature of apoptotic cell death is gross structural changes, one of which is the loss of cell–cell contacts. The caspases, executioners of apoptosis, were shown to cleave several proteins involved in the formation of cell junctions. The membrane-associated guanylate kinases (MAGUKs), which a...

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Detalles Bibliográficos
Autores principales: Ivanova, S, Gregorc, U, Vidergar, N, Javier, R, Bredt, D S, Vandenabeele, P, Pardo, J, Simon, M M, Turk, V, Banks, L, Turk, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077288/
https://www.ncbi.nlm.nih.gov/pubmed/21368887
http://dx.doi.org/10.1038/cddis.2010.92