Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration

Ion fluxes at the plasma membrane have an important role in early stages of apoptosis. Accordingly, plasma membrane depolarization and gain of Na(+) and loss of K(+) are initial events in apoptosis. We have studied the effect of staurosporine (STS), a well-established apoptosis inducer, on the membr...

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Detalles Bibliográficos
Autores principales: Benítez-Rangel, E, García, L, Namorado, M C, Reyes, J L, Guerrero-Hernández, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077289/
https://www.ncbi.nlm.nih.gov/pubmed/21368885
http://dx.doi.org/10.1038/cddis.2010.93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077289/
https://www.ncbi.nlm.nih.gov/pubmed/21368885
http://dx.doi.org/10.1038/cddis.2010.93

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