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A rare case of t(11;22) in a mantle cell lymphoma like B-cell neoplasia resulting in a fusion of IGL and CCND1: case report

The chromosomal translocation (11;14)(q13;q32) rearranging the locus for cyclin D1 (CCND1) to that of the immunoglobulin heavy chain (IGH) can be found in virtually all cases of mantle cell lymphoma (MCL), while other CCND1 translocations are extremely rare. As CCND1 overexpression and activation is...

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Detalles Bibliográficos
Autores principales: Rocha, Cristiano Krings, Praulich, Inka, Gehrke, Iris, Hallek, Michael, Kreuzer, Karl-Anton
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077317/
https://www.ncbi.nlm.nih.gov/pubmed/21457541
http://dx.doi.org/10.1186/1755-8166-4-8