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Human Cytomegalovirus IE1 Protein Elicits a Type II Interferon-Like Host Cell Response That Depends on Activated STAT1 but Not Interferon-γ

Human cytomegalovirus (hCMV) is a highly prevalent pathogen that, upon primary infection, establishes life-long persistence in all infected individuals. Acute hCMV infections cause a variety of diseases in humans with developmental or acquired immune deficits. In addition, persistent hCMV infection...

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Detalles Bibliográficos
Autores principales: Knoblach, Theresa, Grandel, Benedikt, Seiler, Jana, Nevels, Michael, Paulus, Christina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077363/
https://www.ncbi.nlm.nih.gov/pubmed/21533215
http://dx.doi.org/10.1371/journal.ppat.1002016