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Structure-Function Analysis of the Anopheles gambiae LRIM1/APL1C Complex and its Interaction with Complement C3-Like Protein TEP1

Malaria threatens half the world's population and exacts a devastating human toll. The principal malaria vector in Africa, the mosquito Anopheles gambiae, encodes 24 members of a recently identified family of leucine-rich repeat proteins named LRIMs. Two members of this family, LRIM1 and APL1C,...

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Detalles Bibliográficos
Autores principales: Povelones, Michael, Upton, Leanna M., Sala, Katarzyna A., Christophides, George K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077365/
https://www.ncbi.nlm.nih.gov/pubmed/21533217
http://dx.doi.org/10.1371/journal.ppat.1002023