Exosomes Released from M.tuberculosis Infected Cells Can Suppress IFN-γ Mediated Activation of Naïve Macrophages

BACKGROUND: Macrophages infected with Mycobacterium tuberculosis (M.tb) are known to be refractory to IFN-γ stimulation. Previous studies have shown that M.tb express components such as the 19-kDa lipoprotein and peptidoglycan that can bind to macrophage receptors including the Toll-like receptor 2...

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Detalles Bibliográficos
Autores principales: Singh, Prachi P., LeMaire, Christopher, Tan, John C., Zeng, Erliang, Schorey, Jeffery S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077381/
https://www.ncbi.nlm.nih.gov/pubmed/21533172
http://dx.doi.org/10.1371/journal.pone.0018564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077381/
https://www.ncbi.nlm.nih.gov/pubmed/21533172
http://dx.doi.org/10.1371/journal.pone.0018564

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