Cargando…

Exosomes Released from M.tuberculosis Infected Cells Can Suppress IFN-γ Mediated Activation of Naïve Macrophages

BACKGROUND: Macrophages infected with Mycobacterium tuberculosis (M.tb) are known to be refractory to IFN-γ stimulation. Previous studies have shown that M.tb express components such as the 19-kDa lipoprotein and peptidoglycan that can bind to macrophage receptors including the Toll-like receptor 2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Prachi P., LeMaire, Christopher, Tan, John C., Zeng, Erliang, Schorey, Jeffery S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077381/ https://www.ncbi.nlm.nih.gov/pubmed/21533172 http://dx.doi.org/10.1371/journal.pone.0018564

Ejemplares similares

Whole genome sequencing of M.tuberculosis in Kazakhstan: preliminary data
por: Kairov, Ulykbek, et al.
Publicado: (2014)

MPT 64 Antigen detection for Rapid confirmation of M.tuberculosis isolates
por: Kumar, Vijay GS, et al.
Publicado: (2011)

The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis
por: Chan, Conrad E., et al.
Publicado: (2015)

Evaluation of digital PCR assay in detection of M.tuberculosis IS6110 and IS1081 in tuberculosis patients plasma
por: Lyu, Lingna, et al.
Publicado: (2020)

Contribution of remote M.tuberculosis infection to tuberculosis disease: A 30-year population study
por: Glynn, Judith R., et al.
Publicado: (2023)

Predictive Power of ETRE Polymorphism and Katg463 Mutation to INH-Resistance of M.tuberculosis
por: WEN, Yu-feng, et al.
Publicado: (2015)

Drug resistance and population structure of M.tuberculosis isolates from prisons and communities in Ethiopia
por: Ali, Solomon, et al.
Publicado: (2016)

Functional analysis of an intergenic non-coding sequence within mce1 operon of M.tuberculosis
por: Joon, Monika, et al.
Publicado: (2010)

Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ
por: Rayamajhi, Manira, et al.
Publicado: (2010)

Assessment of the N-PCR Assay in Diagnosis of Pleural Tuberculosis: Detection of M.tuberculosis in Pleural Fluid and Sputum Collected in Tandem
por: Kumar, Parameet, et al.
Publicado: (2010)

Mycobacterium tuberculosis–induced IFN-β production requires cytosolic DNA and RNA sensing pathways
por: Cheng, Yong, et al.
Publicado: (2018)

SEPTIN2 suppresses an IFN-γ-independent, proinflammatory macrophage activation pathway
por: Fu, Beibei, et al.
Publicado: (2023)

Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis‐infected and culture filtrate protein‐treated macrophages
por: Giri, Pramod K., et al.
Publicado: (2010)

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease
por: Ballester-López, Carolina, et al.
Publicado: (2019)

Heparin-Binding-Hemagglutinin-Induced IFN-γ Release as a Diagnostic Tool for Latent Tuberculosis
por: Hougardy, Jean-Michel, et al.
Publicado: (2007)

Diagnosis of latent tuberculosis infection among pediatric household contacts of Iranian tuberculosis cases using tuberculin skin test, IFN- γ release assay and IFN-γ-induced protein-10
por: Ghanaie, Roxana Mansour, et al.
Publicado: (2021)

BCG-Vaccinated Children with Contact to Tuberculosis Patients Show Delayed Conversion of Mycobacterium tuberculosis-Specific IFN-γ Release
por: Owusu, Dorcas O., et al.
Publicado: (2023)

IFNγ: Issuing macrophages a license to kill
por: Bashyam, Hema
Publicado: (2007)

Secreted Rv1768 From RD14 of Mycobacterium tuberculosis Activates Macrophages and Induces a Strong IFN-γ-Releasing of CD4(+) T Cells
por: Yuan, Chun-Hui, et al.
Publicado: (2019)

Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection
por: Smith, Victoria L., et al.
Publicado: (2017)

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling
por: Apriamashvili, Georgi, et al.
Publicado: (2022)

Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling
por: Moreira-Teixeira, Lúcia, et al.
Publicado: (2016)

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages
por: Neehus, Anna-Lena, et al.
Publicado: (2017)

The Effects of HIV on the Sensitivity of a Whole Blood IFN-γ Release Assay in Zambian Adults with Active Tuberculosis
por: Raby, Edward, et al.
Publicado: (2008)

High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis
por: Carrère-Kremer, Séverine, et al.
Publicado: (2016)

Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion
por: Tang, Yimin, et al.
Publicado: (2019)

Evaluation of the performance of the IFN-γ release assay in bovine tuberculosis free herds from five European countries
por: Gomez-Buendia, Alberto, et al.
Publicado: (2023)

Identification of M.tuberculosis-Specific Th1 Cells Expressing CD69 Generated in vivo in Pleural Fluid Cells from Patients with Tuberculous Pleurisy
por: Li, Li, et al.
Publicado: (2011)

M.tuberculosis Mutants Lacking Oxygenated Mycolates Show Increased Immunogenicity and Protective Efficacy as Compared to M. bovis BCG Vaccine in an Experimental Mouse Model
por: Hedhli, Dorsaf, et al.
Publicado: (2013)

Evidence for the existence of IL-4 and IFNγ secreting cells in the T cell repertoire of naive mice
por: Wang, Hui, et al.
Publicado: (1992)

ESAT6-Induced IFNγ and CXCL9 Can Differentiate Severity of Tuberculosis
por: Hasan, Zahra, et al.
Publicado: (2009)

IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure
por: Lu, Lenette L., et al.
Publicado: (2019)

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation
por: Kang, Kyuho, et al.
Publicado: (2019)

Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4(+) and CD8(+) T Cells In Vitro and In Vivo
por: Giri, Pramod K., et al.
Publicado: (2008)

IFN-γ is essential for alveolar macrophage–driven pulmonary inflammation in macrophage activation syndrome
por: Gao, Denny K., et al.
Publicado: (2021)

Evaluation of a New IFN-γ Release Assay for Rapid Diagnosis of Active Tuberculosis in a High-Incidence Setting
por: Li, Gen, et al.
Publicado: (2017)

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
por: Rosain, Jérémie, et al.
Publicado: (2023)

Restoration of IFNγR Subunit Assembly, IFNγ Signaling and Parasite Clearance in Leishmania donovani Infected Macrophages: Role of Membrane Cholesterol
por: Sen, Subha, et al.
Publicado: (2011)

Exosomes Released by Influenza-Virus-Infected Cells Carry Factors Capable of Suppressing Immune Defense Genes in Naïve Cells
por: Zabrodskaya, Yana, et al.
Publicado: (2022)

Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis
por: Sakowski, Erik T., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ibsjm9pfpaqjbt9v8s63a9bukg