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14-3-3 Proteins Regulate Exonuclease 1–Dependent Processing of Stalled Replication Forks

Replication fork integrity, which is essential for the maintenance of genome stability, is monitored by checkpoint-mediated phosphorylation events. 14-3-3 proteins are able to bind phosphorylated proteins and were shown to play an undefined role under DNA replication stress. Exonuclease 1 (Exo1) pro...

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Detalles Bibliográficos
Autores principales: Engels, Kim, Giannattasio, Michele, Muzi-Falconi, Marco, Lopes, Massimo, Ferrari, Stefano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077382/
https://www.ncbi.nlm.nih.gov/pubmed/21533173
http://dx.doi.org/10.1371/journal.pgen.1001367