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Highly Precise and Developmentally Programmed Genome Assembly in Paramecium Requires Ligase IV–Dependent End Joining

During the sexual cycle of the ciliate Paramecium, assembly of the somatic genome includes the precise excision of tens of thousands of short, non-coding germline sequences (Internal Eliminated Sequences or IESs), each one flanked by two TA dinucleotides. It has been reported previously that these g...

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Detalles Bibliográficos
Autores principales: Kapusta, Aurélie, Matsuda, Atsushi, Marmignon, Antoine, Ku, Michael, Silve, Aude, Meyer, Eric, Forney, James D., Malinsky, Sophie, Bétermier, Mireille
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077386/
https://www.ncbi.nlm.nih.gov/pubmed/21533177
http://dx.doi.org/10.1371/journal.pgen.1002049