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LINE-1 Hypomethylation During Primary Colon Cancer Progression

BACKGROUND: Methylation levels of genomic repeats such as long interspersed nucleotide elements (LINE-1) are representative of global methylation status and play an important role in maintenance of genomic stability. The objective of the study was to assess LINE-1 methylation status in colorectal ca...

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Detalles Bibliográficos
Autores principales: Sunami, Eiji, de Maat, Michiel, Vu, Anna, Turner, Roderick R., Hoon, Dave S. B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077413/
https://www.ncbi.nlm.nih.gov/pubmed/21533144
http://dx.doi.org/10.1371/journal.pone.0018884