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LINE-1 Hypomethylation During Primary Colon Cancer Progression
BACKGROUND: Methylation levels of genomic repeats such as long interspersed nucleotide elements (LINE-1) are representative of global methylation status and play an important role in maintenance of genomic stability. The objective of the study was to assess LINE-1 methylation status in colorectal ca...
Autores principales: | Sunami, Eiji, de Maat, Michiel, Vu, Anna, Turner, Roderick R., Hoon, Dave S. B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077413/ https://www.ncbi.nlm.nih.gov/pubmed/21533144 http://dx.doi.org/10.1371/journal.pone.0018884 |
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