Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis s a target, a substrate, and a regulator

Several ribosomal proteins regulate p53 function via modulating MDM2. We recently found that RPS27L, a RPS27 like protein, is a direct p53 inducible target. Here we showed that RPS27 itself is a p53 repressible target. Furthermore, the N-terminal region of either RPS27L or RPS27 binds to MDM2 on the...

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Detalles Bibliográficos
Autores principales: Xiong, Xiufang, Zhao, Yongchao, He, Hongbin, Sun, Yi
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077453/
https://www.ncbi.nlm.nih.gov/pubmed/21170087
http://dx.doi.org/10.1038/onc.2010.569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077453/
https://www.ncbi.nlm.nih.gov/pubmed/21170087
http://dx.doi.org/10.1038/onc.2010.569

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