Cargando…
Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis s a target, a substrate, and a regulator
Several ribosomal proteins regulate p53 function via modulating MDM2. We recently found that RPS27L, a RPS27 like protein, is a direct p53 inducible target. Here we showed that RPS27 itself is a p53 repressible target. Furthermore, the N-terminal region of either RPS27L or RPS27 binds to MDM2 on the...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077453/ https://www.ncbi.nlm.nih.gov/pubmed/21170087 http://dx.doi.org/10.1038/onc.2010.569 |