Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia

Nephronophthisis is the most common genetic cause of end-stage renal failure during childhood and adolescence. Genetic studies have identified disease-causing mutations in at least 11 different genes (NPHP1–11), but the function of the corresponding nephrocystin proteins remains poorly understood. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Liebau, Max C., Höpker, Katja, Müller, Roman U., Schmedding, Ingolf, Zank, Sibylle, Schairer, Benjamin, Fabretti, Francesca, Höhne, Martin, Bartram, Malte P., Dafinger, Claudia, Hackl, Matthias, Burst, Volker, Habbig, Sandra, Zentgraf, Hanswalter, Blaukat, Andree, Walz, Gerd, Benzing, Thomas, Schermer, Bernhard
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077625/
https://www.ncbi.nlm.nih.gov/pubmed/21357692
http://dx.doi.org/10.1074/jbc.M110.165464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077625/
https://www.ncbi.nlm.nih.gov/pubmed/21357692
http://dx.doi.org/10.1074/jbc.M110.165464

Ejemplares similares