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Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia
Nephronophthisis is the most common genetic cause of end-stage renal failure during childhood and adolescence. Genetic studies have identified disease-causing mutations in at least 11 different genes (NPHP1–11), but the function of the corresponding nephrocystin proteins remains poorly understood. T...
Autores principales: | Liebau, Max C., Höpker, Katja, Müller, Roman U., Schmedding, Ingolf, Zank, Sibylle, Schairer, Benjamin, Fabretti, Francesca, Höhne, Martin, Bartram, Malte P., Dafinger, Claudia, Hackl, Matthias, Burst, Volker, Habbig, Sandra, Zentgraf, Hanswalter, Blaukat, Andree, Walz, Gerd, Benzing, Thomas, Schermer, Bernhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077625/ https://www.ncbi.nlm.nih.gov/pubmed/21357692 http://dx.doi.org/10.1074/jbc.M110.165464 |
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