Using iPS cells to investigate cardiac phenotypes in patients with Timothy Syndrome

Individuals with congenital or acquired prolongation of the QT interval, or long QT syndrome (LQTS), are at risk of life threatening ventricular arrhythmia 1, 2. LQTS is commonly genetic in origin but can also be caused or exacerbated by environmental factors1, 3. A missense mutation in the L-type c...

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Detalles Bibliográficos
Autores principales: Yazawa, Masayuki, Hsueh, Brian, Jia, Xiaolin, Pasca, Anca M., Bernstein, Jonathan A., Hallmayer, Joachim, Dolmetsch, Ricardo E.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077925/
https://www.ncbi.nlm.nih.gov/pubmed/21307850
http://dx.doi.org/10.1038/nature09855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077925/
https://www.ncbi.nlm.nih.gov/pubmed/21307850
http://dx.doi.org/10.1038/nature09855

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