Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin

In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset...

Descripción completa

Detalles Bibliográficos
Autores principales: Bossert, Jennifer M., Stern, Anna L., Theberge, Florence R.M., Cifani, Carlo, Koya, Eisuke, Hope, Bruce T., Shaham, Yavin
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077927/
https://www.ncbi.nlm.nih.gov/pubmed/21336273
http://dx.doi.org/10.1038/nn.2758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077927/
https://www.ncbi.nlm.nih.gov/pubmed/21336273
http://dx.doi.org/10.1038/nn.2758

Ejemplares similares