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Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin
In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077927/ https://www.ncbi.nlm.nih.gov/pubmed/21336273 http://dx.doi.org/10.1038/nn.2758 |