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Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

Connexin43 (Cx43) has an important role in skeletal homeostasis, and Cx43 gene (Gja1) mutations have been linked to oculodentodigital dysplasia (ODDD), a human disorder characterized by prominent skeletal abnormalities. To determine the function of Cx43 at early steps of osteogenesis and its role in...

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Detalles Bibliográficos
Autores principales: Watkins, Marcus, Grimston, Susan K., Norris, Jin Yi, Guillotin, Bertrand, Shaw, Angela, Beniash, Elia, Civitelli, Roberto
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078079/
https://www.ncbi.nlm.nih.gov/pubmed/21346198
http://dx.doi.org/10.1091/mbc.E10-07-0571