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Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity

The oncoprotein c-Fos has been commonly found differently expressed in cancer cells. Our previous work showed that mouse cells lacking the immediate-early gene c-fos are hypersensitive to ultraviolet (UVC) light. Here, we demonstrate that in human diploid fibroblasts UV-triggered induction of c-Fos...

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Detalles Bibliográficos
Autores principales: Tomicic, Maja T., Reischmann, Patricia, Rasenberger, Birgit, Meise, Ruth, Kaina, Bernd, Christmann, Markus
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078315/
https://www.ncbi.nlm.nih.gov/pubmed/20976523
http://dx.doi.org/10.1007/s00018-010-0546-9