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C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain
The nematode Caenorhabditis elegans has retained a rudimentary Hedgehog (Hh) signalling pathway; Hh and Smoothened (Smo) homologs are absent, but two highly related Patched gene homologs, ptc-1 and ptc-3, and 24 ptc-related (ptr) genes are present. We previously showed that ptc-1 is essential for ge...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078328/ https://www.ncbi.nlm.nih.gov/pubmed/21215260 http://dx.doi.org/10.1016/j.ydbio.2010.12.035 |