Mitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility

BACKGROUND: Mitochondrial DNA (mtDNA) mutations occur in head and neck squamous cell carcinoma (HNSCC) and are most frequently detected in the displacement-loop (D-loop) region. The D-loop is considered to be important because it controls mitochondrial gene expression and mtDNA replication. There is...

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Detalles Bibliográficos
Autores principales: Challen, C, Brown, H, Cai, C, Betts, G, Paterson, I, Sloan, P, West, C, Birch-Machin, M, Robinson, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078603/
https://www.ncbi.nlm.nih.gov/pubmed/21427725
http://dx.doi.org/10.1038/bjc.2011.96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078603/
https://www.ncbi.nlm.nih.gov/pubmed/21427725
http://dx.doi.org/10.1038/bjc.2011.96

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