TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA

Maintenance of telomeres requires both DNA replication and telomere ‘capping’ by shelterin. These two processes employ two single-stranded DNA (ssDNA)-binding proteins, replication protein A (RPA) and protection of telomeres 1 (POT1). Although RPA and POT1 each have a critical role at telomeres, how...

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Detalles Bibliográficos
Autores principales: Flynn, Rachel Litman, Centore, Richard C., O’Sullivan, Roderick J., Rai, Rekha, Tse, Alice, Songyang, Zhou, Chang, Sandy, Karlseder, Jan, Zou, Lee
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078637/
https://www.ncbi.nlm.nih.gov/pubmed/21399625
http://dx.doi.org/10.1038/nature09772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078637/
https://www.ncbi.nlm.nih.gov/pubmed/21399625
http://dx.doi.org/10.1038/nature09772

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