Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid

BACKGROUND: Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutation in the telomeric copy of SMN gene (SMN1) and clinical severity is in part d...

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Detalles Bibliográficos
Autores principales: Darbar, Illora A, Plaggert, Paulo G, Resende, Maria Bernadete D, Zanoteli, Edmar, Reed, Umbertina C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078847/
https://www.ncbi.nlm.nih.gov/pubmed/21435220
http://dx.doi.org/10.1186/1471-2377-11-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078847/
https://www.ncbi.nlm.nih.gov/pubmed/21435220
http://dx.doi.org/10.1186/1471-2377-11-36

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