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Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid
BACKGROUND: Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutation in the telomeric copy of SMN gene (SMN1) and clinical severity is in part d...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078847/ https://www.ncbi.nlm.nih.gov/pubmed/21435220 http://dx.doi.org/10.1186/1471-2377-11-36 |