Genome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapy

BACKGROUND: DNA transposons have emerged as indispensible tools for manipulating vertebrate genomes with applications ranging from insertional mutagenesis and transgenesis to gene therapy. To fully explore the potential of two highly active DNA transposons, piggyBac and Tol2, as mammalian genetic to...

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Detalles Bibliográficos
Autores principales: Meir, Yaa-Jyuhn J, Weirauch, Matthew T, Yang, Herng-Shing, Chung, Pei-Cheng, Yu, Robert K, Wu, Sareina C-Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078864/
https://www.ncbi.nlm.nih.gov/pubmed/21447194
http://dx.doi.org/10.1186/1472-6750-11-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078864/
https://www.ncbi.nlm.nih.gov/pubmed/21447194
http://dx.doi.org/10.1186/1472-6750-11-28

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