Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

BACKGROUND: The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to speed up the process of evalu...

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Detalles Bibliográficos
Autores principales: Royston, Patrick, Barthel, Friederike M-S, Parmar, Mahesh KB, Choodari-Oskooei, Babak, Isham, Valerie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078872/
https://www.ncbi.nlm.nih.gov/pubmed/21418571
http://dx.doi.org/10.1186/1745-6215-12-81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078872/
https://www.ncbi.nlm.nih.gov/pubmed/21418571
http://dx.doi.org/10.1186/1745-6215-12-81

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