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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit
BACKGROUND: The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to speed up the process of evalu...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078872/ https://www.ncbi.nlm.nih.gov/pubmed/21418571 http://dx.doi.org/10.1186/1745-6215-12-81 |