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Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy

Long-term potentiation (LTP) in nociceptive spinal pathways shares several features with hyperalgesia and has been proposed to be a cellular mechanism of pain amplification in acute and chronic pain states. Spinal LTP is typically induced by noxious input and has therefore been hypothesized to contr...

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Detalles Bibliográficos
Autores principales: Ruscheweyh, Ruth, Wilder-Smith, Oliver, Drdla, Ruth, Liu, Xian-Guo, Sandkühler, Jürgen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078873/
https://www.ncbi.nlm.nih.gov/pubmed/21443797
http://dx.doi.org/10.1186/1744-8069-7-20