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Ret-dependent and Ret-independent mechanisms of Gfl-induced sensitization

BACKGROUND: The GDNF family ligands (GFLs) are regulators of neurogenic inflammation and pain. We have previously shown that GFLs increase the release of the sensory neuron neuropeptide, calcitonin gene-related peptide (CGRP) from isolated mouse DRG. RESULTS: Inhibitors of the mitogen-activated prot...

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Detalles Bibliográficos
Autores principales: Schmutzler, Brian S, Roy, Shannon, Pittman, Sherry K, Meadows, Rena M, Hingtgen, Cynthia M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078874/
https://www.ncbi.nlm.nih.gov/pubmed/21450093
http://dx.doi.org/10.1186/1744-8069-7-22