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P27(Kip1), regulated by glycogen synthase kinase-3β, results in HMBA-induced differentiation of human gastric cancer cells

BACKGROUND: Gastric cancer is the second most common cause of global cancer-related mortality. Although dedifferentiation predicts poor prognosis in gastric cancer, the molecular mechanism underlying dedifferentiation, which could provide fundamental insights into tumor development and progression,...

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Detalles Bibliográficos
Autores principales: Wei, Min, Wang, Zhiwei, Yao, Hongliang, Yang, Zhongyin, Zhang, Qing, Liu, Bingya, Yu, Yingyan, Su, Liping, Zhu, Zhenggang, Gu, Qinlong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078896/
https://www.ncbi.nlm.nih.gov/pubmed/21439087
http://dx.doi.org/10.1186/1471-2407-11-109