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Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation

BACKGROUND: Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis and self-tolerance. The immune suppressive effects of Tregs should however be limited in case effective immunity is required against pathogens or cancer cells. We previously found that the Toll-like receptor...

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Detalles Bibliográficos
Autores principales: van Maren, Wendy WC, Nierkens, Stefan, Toonen, Liza W, Bolscher, Judith M, Sutmuller, Roger PM, Adema, Gosse J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078900/
https://www.ncbi.nlm.nih.gov/pubmed/21435210
http://dx.doi.org/10.1186/1471-2172-12-23