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Latency Antigen α-Crystallin Based Vaccination Imparts a Robust Protection against TB by Modulating the Dynamics of Pulmonary Cytokines

BACKGROUND: Efficient control of tuberculosis (TB) requires development of strategies that can enhance efficacy of the existing vaccine Mycobacterium bovis Bacille Calmette Guerin (BCG). To date only a few studies have explored the potential of latency-associated antigens to augment the immunogenici...

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Detalles Bibliográficos
Autores principales: Dey, Bappaditya, Jain, Ruchi, Khera, Aparna, Gupta, Umesh D., Katoch, V. M., Ramanathan, V. D., Tyagi, Anil K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078913/
https://www.ncbi.nlm.nih.gov/pubmed/21533158
http://dx.doi.org/10.1371/journal.pone.0018773