Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation

Janus kinase 2 (JAK2) initiates signaling from several cytokine receptors and is required for biological responses such as erythropoiesis. JAK2 activity is controlled by regulatory proteins such as Suppressor of Cytokine Signaling (SOCS) proteins and protein tyrosine phosphatases. JAK2 activity is a...

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Detalles Bibliográficos
Autores principales: Sanz, Arturo, Ungureanu, Daniela, Pekkala, Tuija, Ruijtenbeek, Rob, Touw, Ivo P., Hilhorst, Riet, Silvennoinen, Olli
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078918/
https://www.ncbi.nlm.nih.gov/pubmed/21533163
http://dx.doi.org/10.1371/journal.pone.0018522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078918/
https://www.ncbi.nlm.nih.gov/pubmed/21533163
http://dx.doi.org/10.1371/journal.pone.0018522

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