A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators

Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome gene (Blm) deficient embryonic stem (ES) cells provide an opportunity for recessive screening due to frequent loss of heterozygosity. We describe a strategy for isolating r...

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Detalles Bibliográficos
Autores principales: Guo, Ge, Huang, Yue, Humphreys, Peter, Wang, Xiaozhong, Smith, Austin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078921/
https://www.ncbi.nlm.nih.gov/pubmed/21533166
http://dx.doi.org/10.1371/journal.pone.0018189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078921/
https://www.ncbi.nlm.nih.gov/pubmed/21533166
http://dx.doi.org/10.1371/journal.pone.0018189

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