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A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome gene (Blm) deficient embryonic stem (ES) cells provide an opportunity for recessive screening due to frequent loss of heterozygosity. We describe a strategy for isolating r...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078921/ https://www.ncbi.nlm.nih.gov/pubmed/21533166 http://dx.doi.org/10.1371/journal.pone.0018189 |