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An Ad5 [E1-, E2b-]-HER2/neu vector induces immune responses and inhibits HER2/neu expressing tumor progression in Ad5 immune mice

Immunotherapy is a promising approach for the treatment of cancers. Modified Adenovirus 5 (Ad5) vectors have been used as a platform to deliver genes encoding TAA. A major obstacle to Ad5 vector immunotherapy has been the induction of vector immunity following administration or the presence of pre-e...

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Detalles Bibliográficos
Autores principales: Gabitzsch, Elizabeth S., Xu, Younong, Balcaitis, Stephanie, Balint, Joseph P., Jones, Frank R.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079015/
https://www.ncbi.nlm.nih.gov/pubmed/21233857
http://dx.doi.org/10.1038/cgt.2010.82