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Apolipoprotein A-I structural organization in high density lipoproteins isolated from human plasma

High density lipoproteins (HDL) mediate cholesterol transport and protection from cardiovascular disease. Although synthetic HDLs have been studied for 30 years, the structure of human plasma-derived HDL, and its major protein apolipoprotein (apo)A-I, is unknown. We separated normal human HDL into 5...

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Detalles Bibliográficos
Autores principales: Huang, Rong, Gangani D. Silva, R. A., Jerome, W. Gray, Kontush, Anatol, Chapman, M. John, Curtiss, Linda K., Hodges, Timothy J., Davidson, W. Sean
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079355/
https://www.ncbi.nlm.nih.gov/pubmed/21399642
http://dx.doi.org/10.1038/nsmb.2028