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Neurotransmitter/sodium symporter orthologue LeuT has a single high–affinity substrate site
Neurotransmitter/sodium symporters (NSSs) couple the uptake of neurotransmitter with one or more sodium ions(1–3), removing neurotransmitter from the synaptic cleft. NSSs are essential to the function of chemical synapses, are associated with multiple neurological diseases and disorders(4), and are...
Autores principales: | Piscitelli, Chayne L., Krishnamurthy, Harini, Gouaux, Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079577/ https://www.ncbi.nlm.nih.gov/pubmed/21179170 http://dx.doi.org/10.1038/nature09581 |
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