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Solution Structure of a Repeated Unit of the ABA-1 Nematode Polyprotein Allergen of Ascaris Reveals a Novel Fold and Two Discrete Lipid-Binding Sites

BACKGROUND: Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins found only in nematodes. They are synthesized as large, tandemly repetitive polyproteins that are post-translationally cleaved into multiple copies of small lipid binding proteins with virtually identica...

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Detalles Bibliográficos
Autores principales: Meenan, Nicola A. G., Ball, Graeme, Bromek, Krystyna, Uhrín, Dušan, Cooper, Alan, Kennedy, Malcolm W., Smith, Brian O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079579/
https://www.ncbi.nlm.nih.gov/pubmed/21526216
http://dx.doi.org/10.1371/journal.pntd.0001040