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Solution Structure of a Repeated Unit of the ABA-1 Nematode Polyprotein Allergen of Ascaris Reveals a Novel Fold and Two Discrete Lipid-Binding Sites
BACKGROUND: Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins found only in nematodes. They are synthesized as large, tandemly repetitive polyproteins that are post-translationally cleaved into multiple copies of small lipid binding proteins with virtually identica...
Autores principales: | Meenan, Nicola A. G., Ball, Graeme, Bromek, Krystyna, Uhrín, Dušan, Cooper, Alan, Kennedy, Malcolm W., Smith, Brian O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079579/ https://www.ncbi.nlm.nih.gov/pubmed/21526216 http://dx.doi.org/10.1371/journal.pntd.0001040 |
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