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Glycated albumin suppresses glucose-induced insulin secretion by impairing glucose metabolism in rat pancreatic β-cells
BACKGROUND: Glycated albumin (GA) is an Amadori product used as a marker of hyperglycemia. In this study, we investigated the effect of GA on insulin secretion from pancreatic β cells. METHODS: Islets were collected from male Wistar rats by collagenase digestion. Insulin secretion in the presence of...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079599/ https://www.ncbi.nlm.nih.gov/pubmed/21470398 http://dx.doi.org/10.1186/1743-7075-8-20 |