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Glycated albumin suppresses glucose-induced insulin secretion by impairing glucose metabolism in rat pancreatic β-cells

BACKGROUND: Glycated albumin (GA) is an Amadori product used as a marker of hyperglycemia. In this study, we investigated the effect of GA on insulin secretion from pancreatic β cells. METHODS: Islets were collected from male Wistar rats by collagenase digestion. Insulin secretion in the presence of...

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Detalles Bibliográficos
Autores principales:	Shiraki, Takayuki, Miura, Yoshikazu, Sawada, Tokihiko, Okada, Toshie, Sakuraoka, Yuhki, Muto, Takashi, Kubota, Keiichi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079599/ https://www.ncbi.nlm.nih.gov/pubmed/21470398 http://dx.doi.org/10.1186/1743-7075-8-20

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